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【科学60秒】狡猾的沙门氏菌
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Last month's salmonella outbreak got over 1,500 people sick. And one reason salmonella may be such a heavy hitter is that it actually ___1___ our immune response for its own benefit. That's according to a study in the journal Nature.
Bacteria in our gut ___2___ things like sugars and fatty acids, which they can break down either through respiration or fermentation. Respiration provides a bigger energy kick. But it requires oxygen, which is ___3___ in the gut. So most bacteria go the fermentation route.
Except salmonella. Because it’s adapted to use the respiration route. Not with oxygen, but via a sulfur compound—something most bacteria can't do.
The insidious thing is that the sulfur compound the salmonella ___4___ is a by-product of the attack our white blood cells launch against the invaders. So by protecting ourselves, we're also ensuring that salmonella stay well-fed. Because a more inflamed gut allows salmonella bacteria to outcompete good bacteria, and explode in numbers. And the little buggers also use our attempts to ___5___ vomiting and diarrhea. Those are both excellent ways for the bugs to get to their next victims.
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