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【科学60秒】你知道吗?肺也有味觉
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Take a deep breath. Taste anything? Actually, your lungs may. Because scientists have discovered that the same receptors that exist on the tongue to taste bitter substances are also found on the smooth muscle of the lungs.
Researchers were studying the receptors on smooth lung muscles that ___1___ of the airways. That’s when they made the discovery—which was so unexpected that the researchers themselves were ___2___.
Finally, they became convinced that the receptors were really there, though not ___3___ in taste buds as they are on the tongue. The scientists then exposed human and mouse airways to various bitter compounds to gauge the effects.
Many toxic compounds are bitter, so the researchers expected the lung muscle to ___4___ and contract—to compel the breather to move away from whatever was bitter and perhaps toxic. But, in a second surprise, bitter compounds relaxed and opened airways better than any existing asthma drug. The study is in the journal Nature Medicine.
Researchers will continue to search for the role of the receptors. Meanwhile, the work ___5___ in the search for drugs to treat asthma, emphysema or chronic bronchitis.
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